Write an essay about developing a NOVEL monoclonal antibody to treat cancer (NOVEL target) i.e this target does not have a monoclonal antibody treatment yet.
1-How make the antibody, mouse then humanise, human transgenic mice, phage libraries.
2-Mechanism of action- Direct killing, ADCC, CDC, neutralisation, drug or radiolabeled conjugate?
4-Specificity,how you will examine its specificity.
6-Phase I clinical trial, how it will be preformed, then phaseII and phase III
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